Although precision medicine is coming along in leaps and bounds, targeted drug delivery to tumours remains a huge challenge. A variety of nanomaterials, including ligand-conjugated liposomes, exosomes, inorganic nanoparticles and immunoliposomes, can be used to deliver specific drugs but the problem is that it is difficult to maintain the bioactivity of these therapeutics. What is more, they must be oriented in the correct way to efficiently target a cell population of interest. A team of researchers at Xiamen University in China has now developed a biomimetic theranostic ligand-targeted nanoplatform based on bio-functionalized liposome-like nanovesicles (BLNs) containing protein/peptide ligands that overcomes all these problems……….
http://nanotechweb.org/cws/article/tech/70809
