Nanodiagnostics Device Research Team (NDx)
Research scope:
Our team focuses on identification and detection of biomarkers, design of targeting molecules, and integration of nanomaterials with biomolecules to develop highly sensitive biosensors and diagnostic devices for screening and monitoring of diseases including diabetes, kidney disease, cancer, and Alzheimer’s disease.
Core technology
• Identify and detect biomarkers related to diabetes, cancer, kidney disease, and Alzheimer’s disease
• Engineer and produce targeting molecules i.e. aptamer, peptide, protein
• Design, synthesis, surface modification, and bio-conjugation of nanomaterials
• Develop biosensors based on fluorescence, SERS, colorimetry, SPR, E-Chem, and nanopore techniques
• Devices fabrication and integration for bio-sensing and medical diagnostics
Research highlights
• Aptasensors for diabetes screening and monitoring
• Biosensors for kidney disease screening
• SERS based biosensors for chemicals, protein, and cancer cell detection
• Fluorescence dye-doped silica nanoparticles for cancer screening and imaging
• Electrochemical sensors for biomarkers detection
Current research projects
- Development of glycated albumin detection for diabetes mellitus screening and monitoring (SugarAL)
- Nucleic acid detection for medical diagnostic
- Highly sensitive sensor for glycated albumin detection from body fluid
- Development of nanoscale materials for non-enzymatic determination of chemical substance in urine using electrochemical and surface-enhanced Raman scattering techniques
- Development of Electrochemical Biosensors for Multiplex Detection of microRNA for Breast Cancer Screening
- NanosenSERS:Ideal SERS substrate for biomedical diagnostic applications
- NANOTEC-KMUITT RNN on electrochemical sensors, biosensors, ultrasensitive detection, multiplex detection, signal amplification by use of nanomaterials, colorimetry, electrochemistry
- NANOTEC-MU RNN on Translational research in nanotechnology-based diagnostics
- Highly Sensitive Lateral Flow Immunochromatographic Assay with Nanoparticle based-Signal Enhancement and Portable Reader for Target Molecule Detection using Plant Pathogen as a Model.
- System Development of Nanoparticle Based Lateral Flow Immunochromatographic Assay for Influenza Diagnosis